The Dubbo Local Government Area is experiencing a tenfold increase in reported influenza (flu) cases.
So far this year there have been 31 reported cases as compared to three in the same period in 2018.
Reported flu cases across the Western NSW Local Health District (WNSWLHD) had skyrocketed to 1129 as of Wednesday.
In the corresponding period last year, 86 cases were reported.
On Wednesday the WNSWLHD advised of "no reported deaths" from flu in Western NSW this year or in 2018.
Its spokeswoman confirmed higher-than-usual flu activity across the district, which was "in line with activity across Australia".
"Emergency departments are continuing to report higher than usual numbers of presentations for respiratory illnesses and influenza-like illness," she said.
The spokeswoman said "everyone" was being encouraged to get vaccinated against the flu.
"It's never too late while influenza is circulating," she said.
People eligible for free flu vaccinations include children aged from six months to five years, Aboriginal people over the age of six months, pregnant women, people with serious underlying health conditions, and people over the age of 65.
The WNSWLHD spokeswoman told the community how to prevent the spread of flu.
"If you have symptoms of flu it's important to prevent the spread by coughing and sneezing into your elbow, washing your hands regularly and staying home if you're unwell," she said.
The spokeswoman urged people with a fever, cough or runny nose not to visit the elderly.
On Friday NSW Health data revealed 66 confirmed flu deaths in NSW in the six months to June 30, 26 of them occurring in residential care facilities.