Alcohol-related violence and anti-social behavior will be the focus on police in Dubbo and other regional areas this weekend.
From Friday through to Monday, police in the western region will be conducting a high-visibility operation in licensed venues.
As well as anti-social behaviour, police will also be targeting COVID-safety compliance.
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There were 65 people arrested and 68 charges laid last time the operation was held in regional NSW.
Northern Region commander Acting Assistant Commissioner Chad Gillies said everyone should feel comfortable and safe to go out and enjoy the nightlife without being impacted by those who wish to disrupt the peace.
"I continue to encourage young people to look out for your mates while enjoying a night out, know your limits and always have a Plan B for getting home," he said.
"Unfortunately, too often do officers see people who act irresponsibly and not only put themselves in harms way, but those around them - and officers will not hesitate to act upon unlawful behaviour and put those persons before the courts."
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