The pack pedalled into Dubbo on Saturday after completing the longest six-day charity ride in the world.

Organisers are confident the event will raise $86,000 for more rooms at Macquarie Home Stay.

Encounters with people along the vast and dusty landscape of the Orana region highlighted the purpose of the fundraising ride, organised by the Rotary Club of Dubbo South.

Macquarie Home Stay opened in January with 14 rooms for people needing a "home away from home" while seeking medical treatment at Dubbo.

Rotary Club of Dubbo South organising committee chairman Mathew Dickerson said at just about every stop, they met someone who'd had experience with the accommodation facility.

"A woman told us she works at the health services out in Lightning Ridge and Walgett and she was guessing she's referred probably a dozen people down to Macquarie Home Stay already," Mr Dickerson said.

"...One gentleman who spoke to us in Bourke stayed at Home Stay I think for about 12 weeks. He'd had open heart surgery, and just the rehab he needed, he needed that rehab to be going every day or every second day, and it just wasn't practical to travel from Bourke each day obviously.

"He was a long-term resident of Macquarie Home Stay, so when you hear stories like that, it really drives home the significance of it."

Mr Dickerson said the tour had an original target of $100,000 but the drought had had an impact, he said.

"I'd be confident of $86,000, I'm not confident of $90,000 but towards that sort of mark," he said.

"What we found was significant this time was obviously the conditions are very tough, as you travel around the region. Locations in the past that have given us donations still gave us donations, but significantly reduced."

Thirteen riders set out from Dubbo on day one, with cyclists from as far away as Port Macquarie, Double Bay and Marrickville taking their spot beside riders from Canowindra and Dubbo.

They headed north first to Armatree, then on to Coonamble, Walgett, Lightning Ridge, Brewarrina, Bourke, Cobar, Nyngan, Warren, Narromine and finished at Dubbo.

Well-known cycling commentator Mike Tomalaris teamed up with the pack for the final stages of the ride.

When asked if the tour would return, Mr Dickerson suggested on the long weekend in October 2021, he would be "bracing myself again for another similar ride".

"I think it now is well-entrenched in the regional community, and they love the fact that we're out there showing off the community in those areas to people from outside the areas, and it's really an education for people, they like that part of it as well," he said.