According to police people broke into the store about 11pm on July 29.

It's believed they smashed through the glass sliding doors at the entrance of the building, and rode two mobility scooters around the showroom before fleeing.

The store was then again broken into just four days after the first attack, by again smashing through the front glass doors, around 11pm on Monday evening.

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This time however, two mobility scooters were taken from the store and driven around Dubbo, before police located them on Cobbora Road.

Manager of the Aidacare store in Dubbo, John Graham said being targeted twice was "annoying and disparaging".

"To be done once that's just bad luck, but twice, it feels like you've been picked on a bit," he said.

He said the two mobility scooters used to drive around Dubbo were worth $4500 each, and now were completely destroyed.

"We got them back but they're totally wrecked and written off, we can't use them for anything," he said.

The store, which specialises in manufacturing and supplying assistive technology healthcare equipment, only opened in Dubbo in May this year.

Mr Graham said while they were a national company, the cost of a targeted attack like this was high.

"We've had to add on extra expenses because we've had security installed with cameras and everything else, so we can actually pick these people up if they were to do it again," he said.

"It's not just a matter about claiming through insurance [like most people think], every time we claim, our premiums go up. It's not a free for all, it doesn't just cost us nothing."

He said it was also disappointing, as the the onset of COVID had also made getting stock at the store difficult.

"A lot of things are shut down so they're not making things, and so they're not so easily replaced," he said.

"But even if they are making stock, it's not as easy to be delivered."

He said they weren't the only one's suffering due to vandalism, with many other businesses and clubs being targeted over the last few months.

Police confirmed investigations were still under way.

Anyone with information are urged to contact Dubbo Police at 6883 1599 or Crime Stoppers on 1800 333 000.

Information is treated in strict confidence and people are reminded not to report crime via and NSW Police social media pages.