In the Dubbo region, 133 people were busted for speeding, while police arrested seven people for drink-driving and 17 for drug-driving.

There were 16 people charged for seatbelt offences, and four issued infringements for mobile offences.

Police also handed out 67 infringements for a variety of offences which included overtaking dangerously, going through stop signs and other non-speed related offences.

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Western Region traffic inspector, Acting Inspector David Thomas said police worked extra hours during the day and night over the Easter long weekend, for one of the first major road operations since COVID-19 restrictions eased.

"In Summer, people go to the coast, around Easter it's the last chance for people to go camping and go out hunting, and they all come out west," he said.

"So we have a lot of traffic movement and that was represented in what our offences are, but overall we were pretty happy."

Acting Inspector Thomas said while there were no fatalities, there were 22 major traffic crashes in the western region where someone was injured.

"We're still coming across people travelling at absolutely excessive speeds, and we're still coming across people who are drink-driving and who are drug-driving," he said.

"Despite all the media, and despite all the attention that its been given, and despite all the high-profile highway patrol and police on the roads, people still think they can do it and get away with it.

"They just need to have a think about it, and they're not going to get away with it, and it's going to have dramatic affects on their life."

"The reason why we target drink driving and drug driving, is they're overrepresented in fatal accidents.

"Twenty-five per cent of people involved in fatal motor vehicle accidents are found to have drugs in their system. So we're basically trying to get to them before they have an accident."

On Sunday, about 8.30am police were patrolling between Yeoval and Wellington on the McGirr Way when they stopped a vehicle for an RBT. The 40-year-old male driver was taken to Wellington Police Station where he produced a positive alcohol reading of 0.184.

On Sunday about 3.35pm police were patrolling the Castlereagh Highway, when they spotted a vehicle travelling at 174km/h in a 100km/h zone. The driver was issued with an infringement for exceeding a speed over 45km/h and had their licence suspended for six months.

In the western region police conducted 1400 random breath tests and 43 drug tests.

Police issued 744 speeding infringements and 420 for other offences. There were 12 mobile phone offences detected and 67 seatbelt infringements issued.