In December 2019, detectives from the State Crime Command's Drug and Firearms Squad established Strike Force Emerstan to investigate the cultivation and supply of cannabis across the Central West.

Their inquiries uncovered a rural property near Dubbo being used for the cultivation of cannabis.

On Monday, strike force detectives executed a crime scene warrant at a Ballimore property, with assistance from Orana Mid-Western Police District, Western Region Enforcement Squad and the Dog Unit.

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"When officers arrived there they came upon a dedicated cultivated of cannabis, a huge plantation comprising 13 industrial-sized grow houses. There was 2440 cannabis plants growing there but over bad above that, 350 kilograms of drying cannabis head was located strewn throughout the property," Drug and Firearms Squad Commander, Detective Superintendent John Watson said.

He said it had an estimated street value of almost $10 million.

Five men, aged 26, 40, 42, 45 and 52, and two women, aged 34 and 59, were arrested at the property and taken to Dubbo Police Station.

All seven people were charged with cultivate prohibited plant (large commercial quantity cannabis), supply prohibited drug (large commercial quantity) and participate criminal group contribute criminal activity.

The 26-year-old man was also charged with possess prohibited drug.

Police will allege in court that the group were involved in the large-scale cultivation and supply of cannabis across NSW.

All seven were refused bail and are due to appear at Dubbo Local Court on Tuesday.

Detective Superintendent Watson said it was a significant seizure because "all the hard work" had been done in preparation for the drugs to be sold on the streets.

He said more arrests could be expected.

"Just this month alone, NSW Police in conjunction with western region officers have seized more than 540 cannabis plants, in excess of 600 kilos of drying cannabis head, 11 offenders are before the courts and the potentially street value of all that is in excess of $17 million," Detective Superintendent Watson said.

Police are urging anyone with information in relation to the cultivation and supply of cannabis to call Crime Stoppers on 1800 333 000.