Grimes was cleared of a serious ankle injury following the Tigers' tight defeat of West Coast, meaning a match-up against form Lions forward Charlie Cameron remains on the cards.

A decisive five-goal haul in the one-point win against Geelong took Cameron's tally to 52 and equal fourth on the Coleman Medal charts.

Breaking a 12-game losing streak against Richmond would guarantee the merged club's first minor premiership since Fitzroy's in 1913, while a loss could see Brisbane finish between first and fourth depending on other results.

The Tigers would need a win of more than 10 goals, plus other results to go their way, to finish on top of the ladder while a loss could see them drop to as low as fifth.

Brisbane captain Zorko expects Grimes to recover in time to play at the MCG, where the Lions haven't won since 2014.

"It was a pretty nasty roll, but professional athletes get themselves up for big games," Zorko said.

"I really rate him as a player, think he's a fantastic player and taken a lot of the load since (Alex) Rance went down."

Zorko said even if Grimes was able to keep Cameron quiet it wouldn't block all avenues to goal.

"If teams want to put a bit of attention into him I have full confidence in rest of the forward line as a collective we can put a score on the board," Zorko said.

"We're not solely relying on Charlie ... we play a really strong system-based game and don't think it's worked a lot when teams have put a lot of energy into one person."

Australian Associated Press