Nick Vlastuin (calf), Josh Caddy (hamstring) and Jack Graham (suspension) are back for the Tigers on Sunday, while Brandon Ellis, Sam Lloyd and Jacob Townsend have all been dropped.

Instant cult hero Jack Higgins kept his spot after kicking three goals in Richmond's Anzac Day eve win over Melbourne.

Mayne is in for his first game since round three last season and Jarryd Blair has also earned a call-up for the Pies, with Travis Varcoe and Ben Crocker rested after their side's Anzac Day win over Essendon.

The Bombers and Demons each made five changes for their clash at Etihad Stadium in Sunday's early game.

Melbourne hard man Jordan Lewis is back after missing just one game with a broken hand, while key tall Tom McDonald (foot) will play his first AFL match of the season.

Charlie Spargo, Bayley Fritsch and Mitch Hannan are also in, while Jeff Garlett was dropped after kicking just one goal in the past two games.

Dean Kent (hamstring), Christian Petracca (dog bite), Josh Wagner (omitted) and Billy Stretch (omitted) are also out.

Patrick Ambrose, Jayden Laverde, Kobe Mutch, Ben McNiece and Matthew Leuenberger come in for John Worsfold's side, while Tom Bellchambers (rested), Michael Hartley (omitted), Josh Green (hamstring), Josh Begley (knee) and David Myers (rested) depart.

Fremantle host West Coast in Sunday's remaining fixture, with Michael Johnson replacing Matt Taberner (foot) in the Dockers' only change.

The Eagles regained Lewis Jetta while Jack Petruccelle will make his AFL debut.

Mark Hutchings and Jackson Nelson were dropped from the team that defeated Carlton.

Australian Associated Press