The four men and two women were among 11 people arrested after a police strike force investigation into the alleged distribution and sale of methylamphetamine, commonly known as ice.

Another three accused also faced Dubbo Local Court on Wednesday, when the charges against them were adjourned.

Lyall Andrew Kennedy, 33, of Dubbo was the first of the six to face magistrate Gary Wilson on Wednesday.

Kennedy pleaded guilty to supplying a prohibited drug on an ongoing basis and to two counts of supplying a prohibited drug.

Five charges were withdrawn and a number of related charges were referred to the District Court.

Gary Paul Bruce Dunn, 47, of Dubbo pleaded guilty to six counts of supplying a prohibited drug on an ongoing basis.

Sixteen charges were withdrawn and one related charge was referred to the higher court.

Leanne Rachel Stewart, 50, of Wellington pleaded guilty to three counts of supplying a prohibited drug on an ongoing basis and two related charges.

Another 17 charges were withdrawn and three related charges were referred to the District Court.

Bryce Adam Cunynghame, 27, of Wellington pleaded guilty to two counts of supplying prohibited drugs on an ongoing basis.

Seven related charges were withdrawn and a number of related charges were referred to the higher court.

April Louise Jenkins, 37, of Dubbo pleaded guilty to knowingly taking part in the supply of a prohibited drug.

A charge of participate in criminal group was withdrawn.

Kyle Thompson, 31, of Wellington pleaded guilty to one count of supplying prohibited drugs on an ongoing basis.

Eleven related charges were withdrawn and a related charge was referred to the higher court.

All six are due to face the District Court on March 17.

The defence for co-accused Donna Marie Williams confirmed pleas of not guilty to a charge of supplying a prohibited drug and to participate in criminal group contribute criminal activity and the matter was adjourned to February 20.

Twenty-three charges against co-accused Shane Elliott were adjourned to February 22.

Fifteen charges against Jacinta Anne Ross were adjourned to March 8.