Gavin Lockley's Symphony of Australia, performed by the Macquarie Philharmonia, will be on stage to please the ears of all music lovers in the region.

The city is one of three regional destinations, along with Young and Bathurst, chosen to host the performance.

With more than 45 musicians and a choir, artistic director Gavin Lockley said the Symphony incorporated everything.

"It's one of the biggest productions I've ever done," he told the Daily Liberal.

Lockley said The Symphony of Australia would take the audience on a journey through the country's historical moments.

The idea began a few years ago, when he was actually trying to compose an anthem.

"I looked at I Love A Sunburnt Country by Dorothea Mackellar for the inspiration and it just flowed on from there," Lockley said.

The music just flowed from there.

Lockley said along with Dorothea Mackellar, a number of Australia's significant poets had influenced the Symphony of Australia, such as Banjo Paterson and Henry Lawson.

"There was so much rich culture in Australia's history which has been put together by these great minds," he said.

The performance is divided into three sections, starting with the Dreamtime period.

"The Symphony then takes a turn with the arrival of the First Fleet and their journey to Australia," Lockley said.

After the settlement, Lockley said the performance synced into a lament for the fallen in World Wars I and II.

The third section takes a look at migrants moving to Australia and a dissection of various national anthems. Lockley said he was looking forward to the Symphony of Australia's reception from the Dubbo audience.

"The music should and will reach out to everyone in the theatre."