Cancer survivors and their supporters at Dubbo have raised at least $63,000 in an event to give hope for the future.

Almost 400 people in 43 teams took part in the 2014 Orana Relay for Life, some not stopping for about 19 hours.

Starting on Saturday afternoon and then through the dark hours of the night they continued to walk around Dubbo's Victoria Park No. 1 Oval, inspired by loved family and friends who died from the disease.

The candlelight ceremony of hope in the evening was, "as always", the highlight for relay committee chairwoman Karen Isbester.

Trish Taylor, whose husband had a sarcoma before she herself was diagnosed with cancer, spoke to the crowd.

"The survivors and carers, that's what it is all about," Mrs Isbester said.

The leader of a passionate relay committee of about 12 volunteers, Mrs Isbester said the beauty of the relay was that it raised money with the aim to one day "stomp out cancer" and also remember those who died.

"The relay went really well - the preliminary fundraising total is $63,000, which is fantastic and teams will have more to bank yet," she said.

"There were teams that walked all night.

"People were relaying for people they've lost - at 3am when they're tired, they are the reason to keep going."

As well as the solemn there were fun moments, including the appearance of V8 race car driver David Reynolds.

He was on hand to cut the ribbon at the start and took the wheel to give test drives which yielded a donation of $2440 from Clancy Ford, Mrs Isbester said.

Earlier on Saturday volunteer Cathy Neely said a trumpeter played during the survivors and carers lap of honour, creating a different atmosphere from the usual bagpipes.

She said she was overwhelmed by the survivors taking part in the walk, including Jack who has been leukaemia free for a year and was in charge of cutting the cake for the Survivor and Carers Afternoon Tea.

"I'm in awe of how strong the survivors are," she said.

As well as raising money, the relay was also promoting a healthy lifestyle with belly dancing performances, zumba and a demonstration by Dubbo City Physical Culture.

A healthy lunchbox session, 'Eat it to Beat It', was given to provide information on how to get more fruit and vegetables into students' lunch boxes and promote the importance of healthy eating.

Ms Neely said the event could not have taken place without the great committee.

"The committee have done a fantastic job organising everything and Dubbo have been fantastic with their support," she said.